ศาสตราจารย์ปฏิบัติ ดร.ภก.

สุพัฒน์ จิรานุสรณ์กุล

Professor of Practice.Dr.

Supat Jiranusornkul

Expertise: เคมียา การสร้างแบบจำลองโมเลกุลเพื่อการออกแบบและพัฒนาตัวยาใหม่ 
หน่วยงาน
ภาควิชาวิทยาศาสตร์เภสัชกรรม
อีเมล
supat.jira@cmu.ac.th ,supatjira@hotmail.com
การศึกษา
  • 2540, ภ.บ.(เกียรตินิยมอันดับ 1) เภสัชศาสตร์
    มหาวิทยาลัยเชียงใหม่
  • 2544, ภ.ม. เภสัชเคมี
    มหาวิทยาลัยเชียงใหม่
  • 2551, Ph.D. Pharmacy
    The University of Nottingham

งานวิจัย

Google Scholar

Scopus

ข้อมูลจากฐานข้อมูลงานวิจัย

  • 2024, The Binding Mode and Molecular Dynamics of Epigallocatechin and Epigallocatechin Gallate with Human Superoxide Dismutase 1 in Complex with a Naphthalene-Catechol Linked Compound
    Indonesian Journal of Pharmaceutical Science and Technology
  • 2023, Potential use of lapatinib in the treatment of head and neck squamous cell carcinoma
    World Academy of Sciences Journal
  • 2023, Inhibitory effects of Indonesian temu kunci (Boesenbergia rotunda) rhizome extract on nitric oxide synthase production and on the kidneys of Wistar rats
    World Academy of Sciences Journal
  • 2023, The role of catechins of Camellia sinensis leaves in modulating antioxidant enzymes: A review and case study
    Journal of Applied Pharmaceutical Science
  • 2022, Suggested quarantine decision for international travelers in COVID-19 situation in Thailand: A case report
    Chiang Mai University Journal of Natural Sciences
  • 2022, Multitarget-Based Virtual Screening for Identification of Herbal Substances toward Potential Osteoclastic Targets
    Applied Sciences
  • 2022, The Binding of Alpinia galanga Oil and Its Nanoemulsion to Mammal GABAA Receptors Using Rat Cortical Membranes and an In Silico Modeling Platform
    Pharmaceutics
  • 2022, Adverse events related to herbal products used by patients presenting at emergency departments
    European Journal of Translational and Clinical Medicine
  • 2022, Lipid Profile, Antioxidant and Antihypertensive Activity, and Computational Molecular Docking of Diatom Fatty Acids as ACE Inhibitors
    Antioxidants
  • 2022, Potential Anti-Alzheimer Agents from Guanidinyl Tryptophan Derivatives with Activities of Membrane Adhesion and Conformational Transition Inhibitions
    Molecules
  • 2021, Effects on Steroid 5-Alpha Reductase Gene Expression of Thai Rice Bran Extracts and Molecular Dynamics Study on SRD5A2
    Biology
  • 2021, Tentative Peptide-Lipid Bilayer Models Elucidating Molecular Behaviors and Interactions Driving Passive Cellular Uptake of Collagen-Derived Small Peptides
    Molecules
  • 2021, Molecular Modeling for a Comparative Analysis of Interactions Between 2LTRZFP and 2-LTR-Circle Junctions
    International Journal of Peptide Research and Therapeutics
  • 2021, Molecular modeling for potential cathepsin L inhibitor identification as new anti-photoaging agents from tropical medicinal plants
    Journal of Bioenergetics and Biomembranes
  • 2021, Characteristic structural knowledge for morphological identification and classification in meso-scale simulations using principal component analysis
    Polymers
  • 2021, Adverse events related to herbal products used by patients presenting at emergency departments
    European Journal of Translational and Clinical Medicine
  • 2020, Discovery of potential sclerostin inhibitors from plants with loop2 region of sclerostin inhibition by interacting with residues outside Pro-Asn-Ala-Ile-Gly motif
    Journal of Biomolecular Structure and Dynamics
  • 2020, Depletion of ?-sitosterol and enrichment of quercetin and rutin in Cissus quadrangularis Linn fraction enhanced osteogenic but reduced osteoclastogenic marker expression
    BMC Complementary Medicine and Therapies
  • 2020, Synthesis of polymeric hydrogels incorporating chlorhexidine gluconate as antibacterial wound dressings
    Journal of Biomaterials Science, Polymer Edition
  • 2020, Effect of molecular weight of poly(ethylene glycol) as humectant in interpenetrating polymer network hydrogels based on poly(sodium AMPS) and gelatin for wound dressing applications
    International Journal of Polymeric Materials and Polymeric Biomaterials
  • 2019, Molecular modeling investigation of the potential mechanism for phytochemical-induced skin collagen biosynthesis by inhibition of the protein phosphatase 1 holoenzyme
    Molecular and Cellular Biochemistry
  • 2018, A significant mechanism of molecular recognition between bioflavonoids and P-glycoprotein leading to herb-drug interactions
    Toxicology Mechanisms and Methods
  • 2018, Molecular modeling elucidates the cellular mechanism of synaptotagmin-SNARE inhibition: a novel plausible route to anti-wrinkle activity of botox-like cosmetic active molecules
    Molecular and Cellular Biochemistry
  • 2018, Investigation of the Skin Anti-photoaging Potential of Swertia chirayita Secoiridoids Through the AP-1/Matrix Metalloproteinase Pathway by Molecular Modeling
    International Journal of Peptide Research and Therapeutics
  • 2018, Molecular modeling of non-covalent binding of Ligustrum lucidum secoiridoid glucosides to AP-1/matrix metalloproteinase pathway components
    Journal of Bioenergetics and Biomembranes
  • 2018, Discovery of novel potent small natural molecules able to enhance attenuation of the pathobiology of gastric cancer-associated Helicobacter pylori by molecular modeling
    International Journal of Peptide Research and Therapeutics
  • 2017, Insight into the molecular mechanism of P-glycoprotein mediated drug toxicity induced by bioflavonoids: an integrated computational approach
    Toxicology Mechanisms and Methods
  • 2016, 3D-QSAR modelling dataset of bioflavonoids for predicting the potential modulatory effect on P-glycoprotein activity
    Data in Brief
  • 2016, Nucleotide binding domain 1 pharmacophore modeling for visualization and analysis of P-glycoprotein–flavonoid molecular interactions
    Frontiers in Biology
  • 2016, Nucleotide-binding domain 1 modelling: A novel molecular docking approach for screening of P-glycoprotein inhibitory activity of bioflavonoids
    Chemical Data Collections
  • 2014, A novel moisturizer extracted from freshwater macroalga [rhizoclonium hieroglyphicum (C.agardh) k tzing] for skin care cosmetic
    Chiang Mai Journal of Science
  • 2010, Pairwise decomposition of residue interaction energies of single chain Fv with HIV-1 p17 epitope variants
    Molecular Immunology
  • 2009, Designed zinc finger protein interacting with the HIV-1 integrase recognition sequence at 2-LTR-circle junctions
    Protein Science
  • 2008, Destabilization of DNA duplexes by oxidative damage at guanine: implications for lesion recognition and repair
    Journal of Royal Society Interface
  • 2008, Destabilization of DNA duplexes by oxidative damage at guanine: implications for lesion recognition and repair
    Journal of the Royal Society Interface
  • , Synthesis of Amino Acid Derivatives of 6- Aminoquinoline Antimalarial Agents
    Hetrocycles

ข้อมูลจาก Google Scholar

  • 2014, A novel moisturizer extracted from freshwater macroalga [Rhizoclonium hieroglyphicum (C. Agardh) Kützing] for skin care cosmetic
    Chiang Mai J. Sci 41 (5.2), 1195-1207, 2014
  • 2010, Pairwise decomposition of residue interaction energies of single chain Fv with HIV-1 p17 epitope variants
    Molecular immunology 47 (5), 982-990, 2010
  • 2021, Effects on steroid 5-alpha reductase gene expression of Thai rice bran extracts and molecular dynamics study on SRD5A2
    Biology 10 (4), 319, 2021
  • 2014, Extraction, characterization and biological activities of extracts from freshwater macroalga [Rhizoclonium hieroglyphicum (C. Agardh) Kützing] cultivated in Northern Thailand
    Chiang Mai J. Sci 41 (1), 14-26, 2014
  • 2018, In vivo anesthetic effect and mechanism of action of active compounds from Alpinia galanga oil on Cyprinus carpio (koi carp)
    Aquaculture 496, 176-184, 2018
  • 2020, Depletion of β-sitosterol and enrichment of quercetin and rutin in Cissus quadrangularis Linn fraction enhanced osteogenic but reduced osteoclastogenic marker …
    BMC complementary medicine and therapies 20, 1-12, 2020
  • 2008, Destabilization of DNA duplexes by oxidative damage at guanine: implications for lesion recognition and repair
    Journal of The Royal Society Interface 5 (suppl_3), 191-198, 2008
  • 2022, Lipid profile, antioxidant and antihypertensive activity, and computational molecular docking of diatom fatty acids as ACE inhibitors
    Antioxidants 11 (2), 186, 2022
  • 2009, Designed zinc finger protein interacting with the HIV‐1 integrase recognition sequence at 2‐LTR‐circle junctions
    Protein Science 18 (11), 2219-2230, 2009
  • 2020, Synthesis of polymeric hydrogels incorporating chlorhexidine gluconate as antibacterial wound dressings
    Journal of Biomaterials Science, Polymer Edition 31 (7), 895-909, 2020
  • 2017, Estimation of retention time in GC/MS of volatile metabolites in fragrant rice using principle components of molecular descriptors
    Analytical Sciences 33 (11), 1211-1217, 2017
  • 2021, Effect of molecular weight of poly (ethylene glycol) as humectant in interpenetrating polymer network hydrogels based on poly (sodium AMPS) and gelatin for wound dressing …
    International Journal of Polymeric Materials and Polymeric Biomaterials 70 …, 2021
  • 2019, Investigation of the Skin Anti-photoaging Potential of Swertia chirayita Secoiridoids Through the AP-1/Matrix Metalloproteinase Pathway by Molecular Modeling
    International Journal of Peptide Research and Therapeutics 25, 517-533, 2019
  • 2017, Insight into the molecular mechanism of p-glycoprotein mediated drug toxicity induced by bioflavonoids: An integrated computational approach
    Toxicology Mechanisms and Methods 27 (4), 253-271, 2017
  • 2019, Discovery of potential sclerostin inhibitors from plants with loop2 region of sclerostin inhibition by interacting with residues outside Pro-Asn-Ala-Ile-Gly motif
    Journal of Biomolecular Structure and Dynamics, 2019
  • 2018, Molecular modeling elucidates the cellular mechanism of synaptotagmin-SNARE inhibition: a novel plausible route to anti-wrinkle activity of botox-like cosmetic active molecules
    Molecular and Cellular Biochemistry 442, 97-109, 2018
  • 2021, Novel multifunctional ascorbic triazole derivatives for amyloidogenic pathway inhibition, anti-inflammation, and neuroprotection
    Molecules 26 (6), 1562, 2021
  • 2018, Molecular modeling of non-covalent binding of Ligustrum lucidum secoiridoid glucosides to AP-1/matrix metalloproteinase pathway components
    Journal of Bioenergetics and Biomembranes 50, 315-327, 2018
  • 2016, Nucleotide-binding domain 1 modelling: A novel molecular docking approach for screening of P-glycoprotein inhibitory activity of bioflavonoids
    Chemical Data Collections 2, 10-16, 2016
  • 2002, Synthesis of amino acid derivatives of 6-aminoquinoline antimalarial agents
    Heterocycles-Sendai Institute of Heterocyclic Chemistry 56 (1-2), 487-496, 2002