รองศาสตราจารย์ ดร.ภญ.

ชฎารัตน์ อัมพะเศวต

Associate Professor Dr.

Chadarat Ampasavate

Expertise: Nanotechnology and Drug Delivery Pharmaceutical and Cosmeceutical Development Pharmaceutical and Biopharmaceutical analysis Activity and Stability Studies of Natural Products
หน่วยงาน
ภาควิชาวิทยาศาสตร์เภสัชกรรม
อีเมล
chadarat.a@cmu.ac.th ,aimchadarat@windowslive.com
การศึกษา
  • 2534, ปริญญาตรี เภสัชศาสตร์
    มหาวิทยาลัยเชียงใหม่
  • 2537, ปริญญาโท เภสัชเคมี
    จุฬาลงกรณ์มหาวิทยาลัย
  • 2542, ปริญญาเอก Pharmacutical Chemistry
    Kansas University, USA

งานวิจัย

Google Scholar

Scopus

Pharmaceutical chemistry and analysis Natural product activity test and development Targeted drug delivery via nanotechnology (cancer and transdermal delivery) Pharmacokinetics and metabolism

ข้อมูลจากฐานข้อมูลงานวิจัย

  • 2024, Natural stabilizers and nanostructured lipid carrier entrapment for photosensitive compounds, curcumin and capsaicin
    pharmaceutics
  • 2024, Microemulsions and nanoemulsions for topical delivery of Tripeptide-3: from design of experiment to anti-sebum efficacy on facial skin
    Pharmaceutics
  • 2023, Targeting Spike Glycoprotein S1 Mediated by NLRP3 Inflammasome Machinery and the Cytokine Releases in A549 Lung Epithelial Cells by Nanocurcumin
    Pharmaceuticals
  • 2022, Pharmacokinetics and analytical determination of acyclovir in Asian elephant calves (Elephas maximus)
    Veterinary and Animal Science, 2022, 15, 100227
  • 2021, Successful treatment of elephant endotheliotropic herpesvirus infection in an Asian elephant (Elephas maximus) calf by oral acyclovir medication: Case report
    Journal of Veterinary Medical Science
  • 2020, Dermal targeting of Centella asiatica extract using hyaluronic acid surface modified niosomes
    Journal of Liposome Research
  • 2020, Antileukemic Cell Proliferation of Active Compounds from Kaffir Lime (Citrus hystrix) Leaves
    Molecules
  • 2020, Photostability indicating HPLC method validation for the simultaneous determination of active compounds in roasted coffee bean, red chili and turmeric extracts
    ไม่ระบุ
  • 2020, Antileukemic Cell Proliferation of Active Compounds from Kaffir Lime (Citrus hystrix) Leaves. Molecules. 2020;25(6):1300; https://doi.org/10.3390/molecules25061300
    Molecules
  • 2019, FLT3, a Prognostic Biomarker for Acute Myeloid Leukemia (AML): Quantitative Monitoring with a Simple Anti-FLT3 Interaction and Flow Cytometric Method
    Journal of Clinical Laboratory Analysis
  • 2019, FLT3, a Prognostic Biomarker for Acute Myeloid Leukemia (AML): Quantitative Monitoring with a Simple Anti-FLT3 Interaction and Flow Cytometric Method
    J Clin Lab Anal
  • 2018, Natural product for anti-leukemia research: gene expression suppression and drug targeting
    ไม่ระบุ
  • 2018, ระดับของยาทรามาดอลในนมน้ำเหลืองของแม่สุนัขที่ได้รับยาทรามาดอลทางหลอดเลือดดำหลังการผ่าคลอด
    เชียงใหม่สัตวแพทยสาร
  • 2018, Development of curcumin-loaded polymeric micelles as nanocarrier system for leukemia-targeted therapy
    ไม่ระบุ
  • 2009, HPLC Determination of Mangostin and Its Application to Storage Stability Study
    Chiang Mai University Journal of Natural Sciences
  • 2008, Bioequivalence Study Doxazosin Tablets in Healthy Thai Male Volunteers
    Thai Journal of Pharmacology
  • 2008, Bioequivalence Study of Cefoperazone+Sulbactam (Sulpermed? and Sulperazon?) Im Injections in Healthy Thai Male Volunteers
    เภสัชกรรมคลินิก
  • 2008, PLGA Nanoparticle-Peptide Conjugate Effectively Targets Intercellular Cell-Adhesion Molecule-1
    Bioconjug Chem
  • 2008, Bioequivalence Study of the Two 1.5g Cefoperazone and Sulbactam IM Injections in Thai Healthy Male Volunteers
    Journal of the Medical Association of Thailand
  • 2008, Acute and Repeted Dose 28-Day Oral Toxicity Study of Garcinia mangostana Linn. Rind Extract
    Chiang Mai University Journal of Natural Sciences
  • 2008, Bioequivalence study of the two 1.5 g cefoperazone and sulbactam IM injections in Thai healthy male volunteers
    Journal of the Medical Association of Thailand
  • 2007, Bioequivalence Study of Ampicillin and Sulbactam Combination in Healthy Thai Male Volunteers
    เภสัชกรรมคลินิก
  • 2007, Bioequivalence Study of Fexofenadine Tablet (Fenafex?and Telfast?)
    เภสัชกรรมคลินิก
  • 2007, Effect of pure curcumin, demethoxycurcumin, and bisdemethoxycurcumin on WT1 gene expression in leukemic cell lines.
    Cancer Chemother Pharmacol
  • 2006, Comparison of antioxidant capacities and cytotoxicities of certain fruit peels
    Food Chemistry
  • 2006, Bioequivalence Study of Fexofenadine Tablet (Fenafex? and Telfast?)
    ตอบรับให้ตีพิมพ์ในวารสารเภสัชกรรมคลินิก
  • 2005, Bioequivalence Study of Cefoperazone + Sulbactam IM Injections
    วารสารเภสัชกรรมคลินิค
  • , Peptide transport and metabolism across the placenta
    Advance Drug Delivery Reviews
  • , The Fourteenth Graduate Honors Seminar Program, School of Pharmacy
    ไม่ระบุ
  • , The 19th Health Science Conference
    ไม่ระบุ
  • , The 19th Health Science Conference
    ไม่ระบุ
  • , The 19th Annual Health Sciences Meeting
    ไม่ระบุ
  • , การศึกษาชีวสมมูลของยาเม็ดเซทิริซีน(Cetirizine)
    เภสัชกรรมคลินิก
  • , The 19th Annual Health Sciences Meeting
    ไม่ระบุ
  • , The 19th Annual Health Sciences Meeting
    ไม่ระบุ
  • , Bioequivalence Study of Cetririzine Tablets
    Clinical Pharmacy
  • , Transport and Metabolism of Opioid Peptides Across Bewo Cells, an In Vitro Model of The Placental Barrier
    International Journal of Pharmaceutics
  • , การศึกษาชีวสมมูลของยาเม็ดเซทิริซีน (Cetirizine)
    วารสารเภสัชกรรมคลินิก
  • , การศึกษาชีวสมมูลของยาเม็ดเซทิริซีน (Cetirizine)
    วารสารเภสัชกรรมคลินิก
  • , Bioequivalence Studies of Itraconazole Capsules
    Thai J Dermatol
  • , Preliminary Screening of some Rubiaceous Plants for Cytotoxic Activity Against Cervix Carcinoma (KB-3-1) Cell Line
    Thai Journal of Pharmaceutical Science
  • , The 2nd International Conference on Medicinal Mushroom and the International Conference on Biodiverstiy and Bioactive Compounds
    ไม่ระบุ

ข้อมูลจาก Google Scholar

  • 2012, Enhancement of cellular uptake and cytotoxicity of curcumin-loaded PLGA nanoparticles by conjugation with anti-P-glycoprotein in drug resistance cancer cells
    Acta Pharmacologica Sinica 33 (6), 823-831, 2012
  • 2010, Investigation of fruit peel extracts as sources for compounds with antioxidant and antiproliferative activities against human cell lines
    Food and Chemical Toxicology 48 (8-9), 2122-2129, 2010
  • 2010, Demethoxycurcumin suppresses migration and invasion of MDA-MB-231 human breast cancer cell line
    European journal of pharmacology 627 (1-3), 8-15, 2010
  • 2011, Stemona alkaloids, from traditional Thai medicine, increase chemosensitivity via P-glycoprotein-mediated multidrug resistance
    Phytomedicine 18 (2-3), 199-204, 2011
  • 2010, Cytotoxicity of extracts from fruit plants against leukemic cell lines
    Afr. J. Pharm. Pharmacol 4 (1), 13-21, 2010
  • 2010, The inhibitory effect of turmeric curcuminoids on matrix metalloproteinase-3 secretion in human invasive breast carcinoma cells
    Archives of pharmacal research 33, 989-998, 2010
  • 2010, Effects of Curcuma spp. on P-glycoprotein function
    Phytomedicine 17 (7), 506-512, 2010
  • 2010, LFA-1 on leukemic cells as a target for therapy or drug delivery
    Current pharmaceutical design 16 (21), 2321-2330, 2010
  • 2011, Cytotoxic effects of crude kaffir lime (Citrus hystrix, DC.) leaf fractional extracts on leukemic cell lines
    J Med Plants Res 5 (14), 3097-3105, 2011
  • 2020, Enhanced transdermal delivery of concentrated capsaicin from chili extract-loaded lipid nanoparticles with reduced skin irritation
    Pharmaceutics 12 (5), 463, 2020
  • 2017, Stable curcumin-loaded polymeric micellar formulation for enhancing cellular uptake and cytotoxicity to FLT3 overexpressing EoL-1 leukemic cells
    European Journal of Pharmaceutics and Biopharmaceutics 114, 57-68, 2017
  • 2002, Transport and metabolism of opioid peptides across BeWo cells, an in vitro model of the placental barrier
    International journal of pharmaceutics 233 (1-2), 85-98, 2002
  • 1999, Peptide transport and metabolism across the placenta
    Advanced drug delivery reviews 38 (1), 59-67, 1999
  • 2020, Dermal targeting of Centella asiatica extract using hyaluronic acid surface modified niosomes
    Journal of liposome research 30 (2), 197-207, 2020
  • 2020, Antileukemic Cell Proliferation of Active Compounds from Kaffir Lime (Citrus hystrix) Leaves
    Molecules 25 (6), 1300, 2020
  • 2014, Inhibitory effect of turmeric curcuminoids on FLT3 expression and cell cycle arrest in the FLT3-overexpressing EoL-1 leukemic cell line
    Journal of natural products 77 (4), 948-954, 2014
  • 2011, Anti-P-glycoprotein conjugated nanoparticles for targeting drug delivery in cancer treatment
    Archives of pharmacal research 34, 1679-1689, 2011
  • 2011, Killing kinetics and bactericidal mechanism of action of Alpinia galanga on food borne bacteria
    African J Microbiol Res 5 (18), 2847-2854, 2011
  • 2016, Development and characterization of FLT3-specific curcumin-loaded polymeric micelles as a drug delivery system for treating FLT3-overexpressing leukemic cells
    Journal of pharmaceutical sciences 105 (12), 3645-3657, 2016
  • 2012, Pharmacokinetics of ganoderic acids A and F after oral administration of Ling Zhi preparation in healthy male volunteers
    Evidence‐Based Complementary and Alternative Medicine 2012 (1), 780892, 2012