รองศาสตราจารย์ ดร.ภญ.

ชฎารัตน์ อัมพะเศวต

Associate Professor Dr.

Chadarat Ampasavate

Expertise: Nanotechnology and Drug Delivery Pharmaceutical and Cosmeceutical Development Pharmaceutical and Biopharmaceutical analysis Activity and Stability Studies of Natural Products
หน่วยงาน
ภาควิชาวิทยาศาสตร์เภสัชกรรม
อีเมล
chadarat.a@cmu.ac.th ,aimchadarat@windowslive.com
การศึกษา
  • 2534, ปริญญาตรี เภสัชศาสตร์
    มหาวิทยาลัยเชียงใหม่
  • 2537, ปริญญาโท เภสัชเคมี
    จุฬาลงกรณ์มหาวิทยาลัย
  • 2542, ปริญญาเอก Pharmacutical Chemistry
    Kansas University, USA

งานวิจัย

Google Scholar

Scopus

Pharmaceutical chemistry and analysis Natural product activity test and development Targeted drug delivery via nanotechnology (cancer and transdermal delivery) Pharmacokinetics and metabolism

ข้อมูลจาก Google Scholar

  • 2012, Enhancement of cellular uptake and cytotoxicity of curcumin-loaded PLGA nanoparticles by conjugation with anti-P-glycoprotein in drug resistance cancer cells
    Acta Pharmacologica Sinica 33 (6), 823-831, 2012
  • 2010, Investigation of fruit peel extracts as sources for compounds with antioxidant and antiproliferative activities against human cell lines
    Food and Chemical Toxicology 48 (8-9), 2122-2129, 2010
  • 2010, Demethoxycurcumin suppresses migration and invasion of MDA-MB-231 human breast cancer cell line
    European journal of pharmacology 627 (1-3), 8-15, 2010
  • 2010, Cytotoxicity of extracts from fruit plants against leukemic cell lines
    Afr. J. Pharm. Pharmacol 4 (1), 13-21, 2010
  • 2011, Stemona alkaloids, from traditional Thai medicine, increase chemosensitivity via P-glycoprotein-mediated multidrug resistance
    Phytomedicine 18 (2-3), 199-204, 2011
  • 2010, The inhibitory effect of turmeric curcuminoids on matrix metalloproteinase-3 secretion in human invasive breast carcinoma cells
    Archives of pharmacal research 33, 989-998, 2010
  • 2010, Effects of Curcuma spp. on P-glycoprotein function
    Phytomedicine 17 (7), 506-512, 2010
  • 2020, Enhanced transdermal delivery of concentrated capsaicin from chili extract-loaded lipid nanoparticles with reduced skin irritation
    Pharmaceutics 12 (5), 463, 2020
  • 2010, LFA-1 on leukemic cells as a target for therapy or drug delivery
    Current pharmaceutical design 16 (21), 2321-2330, 2010
  • 2011, Cytotoxic effects of crude kaffir lime (Citrus hystrix, DC.) leaf fractional extracts on leukemic cell lines
    J Med Plants Res 5 (14), 3097-3105, 2011
  • 2020, Dermal targeting of Centella asiatica extract using hyaluronic acid surface modified niosomes
    Journal of liposome research 30 (2), 197-207, 2020
  • 2020, Antileukemic Cell Proliferation of Active Compounds from Kaffir Lime (Citrus hystrix) Leaves
    Molecules 25 (6), 1300, 2020
  • 2017, Stable curcumin-loaded polymeric micellar formulation for enhancing cellular uptake and cytotoxicity to FLT3 overexpressing EoL-1 leukemic cells
    European Journal of Pharmaceutics and Biopharmaceutics 114, 57-68, 2017
  • 1999, Peptide transport and metabolism across the placenta
    Advanced drug delivery reviews 38 (1), 59-67, 1999
  • 2002, Transport and metabolism of opioid peptides across BeWo cells, an in vitro model of the placental barrier
    International journal of pharmaceutics 233 (1-2), 85-98, 2002
  • 2011, Anti-P-glycoprotein conjugated nanoparticles for targeting drug delivery in cancer treatment
    Archives of pharmacal research 34, 1679-1689, 2011
  • 2014, Inhibitory effect of turmeric curcuminoids on FLT3 expression and cell cycle arrest in the FLT3-overexpressing EoL-1 leukemic cell line
    Journal of natural products 77 (4), 948-954, 2014
  • 2012, Pharmacokinetics of ganoderic acids A and F after oral administration of Ling Zhi preparation in healthy male volunteers
    Evidence‐Based Complementary and Alternative Medicine 2012 (1), 780892, 2012
  • 2011, Killing kinetics and bactericidal mechanism of action of Alpinia galanga on food borne bacteria
    African J Microbiol Res 5 (18), 2847-2854, 2011
  • 2019, FLT3-specific curcumin micelles enhance activity of curcumin on FLT3-ITD overexpressing MV4-11 leukemic cells
    Drug Development and Industrial Pharmacy 45 (3), 498-505, 2019